OxyContin was neither superior to old-fashioned immediate-release oxycodone, a cheaper generic, nor did it offer any advantage over other opioids like morphine.
Kratom is a a highly addictive, unregulated drug. It has been brought into the US by importers, often via illegal routes, for the last decade and is frequently seized by the FDA and destroyed
Amphetamine was synthesized from ephedrine by German scientists in 1887, and methamphetamine, also created by Nagayoshi, arrived in 1893. Pharmacologist Akira Ogata took methamphetamine one step further
