Heart and blood vessel diseases are serious problems, with one of the leading causes of death for individuals 65 and older being heart disease¹. While lifestyle plays an essential role in keeping individuals healthy, sometimes changes are not always possible, or people have a particularly high-risk profile. It is for these individuals that the class of medication called statins is considered.
Statins are medications that are used to control one’s cholesterol levels. They increase HDL and decrease LDL², the so-called good and bad cholesterol (refer to Points of Curiosity for more information).
Clinical trials have demonstrated that statins decrease one’s risk of having a heart attack or stroke². High total cholesterol or too much LDL cholesterol is problematic because they contribute to blood vessels’ blockage. Statins decrease the amount of cholesterol typically made in the body to better manage the excess deposits in less than ideal places.
The vast majority of individuals who take statins have no adverse effects from the medication². The most common adverse effect is the muscles being sore². This adverse effect has a greater chance of occurring with higher doses of the medication². If you are experiencing such symptoms, you can talk with your doctor to discuss what to do next. Decreasing the dose may resolve the symptoms while continuing to protect against stroke and heart attack.
Rarely, those with affected muscles can develop rhabdomyolysis, where muscle cells die and release their contents into the blood². This can cause an acute kidney injury that may require hospitalization. It is best if statins are not taken with other medications that can cause muscle pathology as it increases the risk of this complication². Individuals may also rarely have evidence of liver injury². This is typically temporary and goes away without complications.
Ultimately, this is often a question that requires consideration of an individual’s determined benefit of the medication compared to risk, as determined by their personal doctor. It is advised to avoid taking statins when one has active liver disease². They should also not be taken during pregnancy or while breast feeding².
The most commonly prescribed statins are atorvastatin, lovastatin, pravastatin, and simvastatin. Note how the end of the names of each of these medications is a statin.
While HDL and LDL are known as good and bad cholesterol, it is more complicated than that. LDL plays a role in routine body maintenance. It can also cause problems if there is too much of it.
The San Antonio Breast Cancer Symposium (SABCS) is one of the largest gatherings where researchers,…
It is impossible to talk about and predict the future without considering past events. Therefore,…
Years ago, I had enough experience to understand that some certificates on people’s walls might…
Although rare by definition, the collective impact of rare diseases is anything but insignificant. In the…
People often discover these businesses through online advertisements while they drive past shopping centers. The…
For more than three years, I have been working on a simple but powerful question:…
This website uses cookies. Your continued use of the site is subject to the acceptance of these cookies. Please refer to our Privacy Policy for more information.
Read More